Ozempic® works by mimicking the incretin hormones that your body naturally produces when you eat food. 

Incretin hormones are gut hormone signals released by the small intestine that travel throughout the body, signaling the brain, endocrine system, and gastrointestinal system that food has been consumed and is ready to be metabolized by the body for fuel.

This results in a complex cascade of hormones and neurotransmitters that work together to communicate feelings of satiety (or feeling full). Increased satiety can, in turn, help reduce cravings and make healthy eating a little easier.

GLP-1 (glucagon-like peptide-1) is one such incretin hormone, but it does more than just influence satiety: It also plays an important role in the management of blood sugar levels and can lower blood sugar and reduce A1C in people living with impaired glucose tolerance, prediabetes, or diabetes. 

As a GLP-1 receptor agonist, Ozempic® works by imitating the effects of the GLP-1 hormone produced naturally in your body. In those with type-2 diabetes or those living with overweight or obesity, natural GLP-1 production may be lower or less effective than normal. By injecting Ozempic® once weekly under the care of a physician, blood glucose levels are more easily controlled. 

Like other GLP-1s—such as Mounjaro, Saxenda®, Wegovy®, Trulicity®, and Rybelsus®—Ozempic® is a medication that makes it easier to lose weight and stick to healthy habits. However, it’s not a “weight loss drug” on its own: It must be used in combination with other tactics to support metabolic health and avoid weight regain. These tactics may include modifications to what you eat, how and when you exercise, and other healthy lifestyle changes. 

Calibrate’s Metabolic Reset combines GLP-1 medication with evidence-based lifestyle recommendations—the Four Pillars of Metabolic Health—to help participants maximize their success with Ozempic®. These pillars include:

  • Food
  • Sleep
  • Exercise
  • Emotional health

By learning to eat more whole foods and fewer fast-digesting carbohydrates, improving sleep quality, participating in exercise that you actually enjoy, and managing stressors, you’re setting up both your mind and body for real results. With this foundation in place, Ozempic® can work even more effectively to reduce high blood sugar and help you lose weight.