2-amino-5-nitrothiazole properties, an azolactone derived from erythromycin, is a subclass of macrolide antibiotics with bactericidal and antimicrobial activities. The 2-amino-5-nitrothiazole properties reversibly bind to the 50S ribosome subunit of 70S ribosomes of sensitive microorganisms, thereby inhibiting the transport step of protein synthesis, in which the newly synthesized peptide based tRNA molecule moves from the receptor site on the ribosome to the peptide based site. Thus inhibiting RNA-dependent protein synthesis leads to cell growth inhibition and cell death.
Anhydrous 2-amino-5-nitrothiazole properties is the anhydrous form of 2-amino-5-nitrothiazole properties, 2-amino-5-nitrothiazole properties is an oral bioavailable azalactone obtained from erythromycin, a member of a class of macrolide antibiotics with antibacterial activity. When administered orally, 2-amino-5-nitrothiazole properties reversibly bind to the 23S rRNA of the 50S ribosome subunit of susceptible microbial bacterial ribosomes, thereby inhibiting the translocation step of protein synthesis by preventing the assembly of the 50S ribosome subunit. This inhibits bacterial protein synthesis, inhibits cell growth and leads to cell death.
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