Hydrocodone Hydrocodone is an antitussive (cough suppressant) and narcotic analgesic agent to remedy slightly intense aches. Studies suggest that hydrocodone is as effective, or extra practical, as codeine for cough suppression and almost equipotent to morphine for ache relief. Is hydrocodone acetaminophen over the counter? Hydrocodone is a painkiller inside the opioid family (associated...